

RS2/MIRABILUS® GOLA
Functionality of the upper airways
RS2/MIRABILUS ® THROAT supports the body in case of sore throat, pharyngitis, laryngitis and all discomforts related to the upper respiratory tract. Thanks to the active ingredients present, it acts as an antimicrobial and promotes immune defenses, counteracting the risk factors that predispose to seasonal ailments.


Glass spray bottle 30 ml.

We recommend 2 spray jets 4 times a day. For children aged 3 to 9 years, halve the dosage.

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Additional Information
NO PRESERVATIVES / NO GLUTEN / NATURALLY LACTOSE-FREE / FOR VEGETARIANS / WITH SWEETENER
The possible variation in flavor between different production batches of the same product is due to the use of natural raw materials that can offer different aromas to the palate based on seasonal climatic conditions.
Device of interest:
Respiratory System
Packaging:
30 ml glass spray bottle
How to use:
It is recommended to use 2 spray doses 4 times a day. For children aged 3 to 9 years, the dosage is halved.
Storage conditions:
Close the container after use, store away from light.
Warnings: Do not exceed the recommended daily dose. Food supplements should not be considered as substitutes for a varied and balanced diet and a healthy lifestyle. Keep out of reach of children under 3 years old. The possible presence of sediment is a consequence of using natural origin ingredients, which does not affect the quality of the product.
Ingredients
Echinacea angustifolia DC. root e.f.; Glycyrrhiza glabra L. root e.f.; Citrus paradisi (L.) Macfad seed e.f.; Italian honey; Italian propolis TM; Flavourings: mint and liquorice; Lecithin Soy; Sweetener: Stevia Rebaudiana; Melaleuca alternifolia (Maiden & Betche) Chee o.e.; Mentha x piperita L. o.e.
Daily dose content
Echinacea:
87 mg plant in e.f.
Honey
537 mg
Licorice
87 mg plant in e.f.
Tea Tree o.e.:
3,48 mg
Italian propolis TM
537mg
Mint o.e.
3,48 mg
Grapefruit seeds
11.6 mg plant in e.f.


Bioenergetic Extraction® patent
Natural products obtained exclusively from plant extracts. A unique and innovative methodology.

High Quality
Maintains the organoleptic and health properties of the plants, thanks to ultrasonic maceration and low temperatures.

Absence of additives
We do not use excipients, sweeteners, surfactants or emulsifiers, guaranteeing a purer product.

RS2/MIRABILUS® THROAT
RS2/MIRABILUS®GOLA supports the organism in case of ache throat, pharyngitis, laryngitis and all the discomforts related to the upper respiratory tract. In fact, in the winter periods and where the humid seasons favor the onset of problems related to the upper airways, the set of active ingredients present in the natural phytocomplex, including Echinacea, Italian Honey, Propolis Italian, Licorice ed Extracts of Grapefruit seeds, acts as antimicrobial and promotes immune defenses, counteracting the risk factors that predispose to seasonal ailments. An excellent supplement for sore throats if taken at the onset of viral symptoms, it helps to reduce the intensity and duration of the ailment. It is recommended to take it by combining it with the other products in the MIRABILUS line®.
Properties of natural elements
Echinacea
Echinacea is a perennial Asteraceae, used as an immune system stimulant in the prevention of upper respiratory infections and as support for related therapies. This immunostimulatory function is linked to the ability to activate macrophages, which in turn regulate the activity of the pro-inflammatory cytokines IL-6, IL-8, and TNF-alpha, resulting in the elimination of the toxic agent. Furthermore, it has been shown that the alkylamides present in the plant bind to cannabinoid receptors, thereby developing an immunomodulatory effect. Also interesting are the studies that have demonstrated antibacterial activity against Escherichia Coli and Pseudomonas Aeruginosa.
Sources:
Assessment report on Echinacea purpurea radix. EMA/MPC/424584/2016
Grapefruit Seed Extracts
grapefruit is a fruit rich in vitamins, minerals, flavonoids and with antibacterial and antimicrobial properties. Its strength against bacteria lies precisely in the diversification of the mechanism of action it exerts: it acts directly on bacteria by attacking the cell membrane. The microorganisms, deprived of their external protection, they suffer damage to the cytoplasm and become unable to survive the surrounding environment. This mechanism slowly causes them to die. It acts on yeasts by causing a process called apoptosis, which causes the cells to self-destruct.
Due to its ability to act, grapefruit seed extract is considered an excellent antibacterial, antiviral and antifungal. Furthermore, the vitamins present within it, A, C, E, also give it notable properties antioxidants.
Sources:
J Altern Complement Med. 2002 Jun;8(3):333-40. The effectiveness of processed grapefruit-seed extract as an antibacterial agent: II. Mechanism of action and in vitro toxicity. Heggers JP, Cottingham J, Gusman J, Reagor L, McCoy L, Carino E, Cox R, Zhao JG
Italian honey
Honey is a very complex substance, rich in vital elements, which make it a real supplement. Made up mainly of sugars, it also contains many mineral salts and vitamins, in particular those of groups B and C, folic acid and pantothenic acid; there are substances with antibiotic action, amino acids, proteins, hormones, enzymes etc. For this reason, honey offers numerous benefits: as a decongestant and calming cough, it increases physical strength and resistance, has a cardiotropic, hepatoprotective and detoxifying action, stimulates and regulates the digestive system, and has an anti-inflammatory action. anemic.
Sources:
Medical benefit of honeybee products. José Mauricio Sforcin, Vassya Bankova, Andrzej K. Kuropatncki. 2017: 2702106
Italian propolis
Propolis is a resinous substance produced by bees, composed of more than 300 components including resins, balms and waxes, which vary depending on the different collection sources. To these components are added aromatic acids, pollen, essential oils, flavonoids and polyphenols, mineral salts and vitamins group B, which make it a true natural medicine. Numerous studies see propolis as the protagonist, as it has anti-inflammatory, antiviral, antimicrobial, antifungal and immunomodulatory activity. Precisely on this last point it has been seen how it modulates at a genetic level the expression of some receptors implicated in the pro-inflammatory cascade and modulates the activity of the macrophages.
Sources:
Búfalo, M. C., Bordon-Graciani, A. P., Conti, B. J., de Assis Golim, M., & Sforcin, J. M. (2014). The immunomodulatory effect of propolis on receptors expression, cytokine production and fungicidal activity of human monocytes. Journal of Pharmacy and Pharmacology, 66(10), 1497–1504
Mint
Mint is a herbaceous, perennial plant, 50-60 cm tall, equipped with a fibrous, branched rhizome. It is a renowned plant used since ancient times, both in culinary and herbal contexts, especially for its menthol content, the most active part of the phytocomplex found in the essential oil. In vitro, it has demonstrated antispasmodic activity on intestinal tissues, inhibiting the spontaneous contractility of the colon by acting on intracellular calcium influx. It is particularly indicated in cases of irritable bowel syndrome. Menthol has also shown broncomucotropic activity, meaning it stimulates the production of cellular mucus at the bronchial level.
Sources:
Assessment report on Mentha piperita aetheroleum. EMA/HMPC/349465/2006
Echinacea is a perennial Asteraceae, used as an immune system stimulant in the prevention of upper respiratory infections and as support for related therapies. This immunostimulatory function is linked to the ability to activate macrophages, which in turn regulate the activity of the pro-inflammatory cytokines IL-6, IL-8, and TNF-alpha, resulting in the elimination of the toxic agent. Furthermore, it has been shown that the alkylamides present in the plant bind to cannabinoid receptors, thereby developing an immunomodulatory effect. Also interesting are the studies that have demonstrated antibacterial activity against Escherichia Coli and Pseudomonas Aeruginosa.
Sources:
Assessment report on Echinacea purpurea radix. EMA/MPC/424584/2016
grapefruit is a fruit rich in vitamins, minerals, flavonoids and with antibacterial and antimicrobial properties. Its strength against bacteria lies precisely in the diversification of the mechanism of action it exerts: it acts directly on bacteria by attacking the cell membrane. The microorganisms, deprived of their external protection, they suffer damage to the cytoplasm and become unable to survive the surrounding environment. This mechanism slowly causes them to die. It acts on yeasts by causing a process called apoptosis, which causes the cells to self-destruct.
Due to its ability to act, grapefruit seed extract is considered an excellent antibacterial, antiviral and antifungal. Furthermore, the vitamins present within it, A, C, E, also give it notable properties antioxidants.
Sources:
J Altern Complement Med. 2002 Jun;8(3):333-40. The effectiveness of processed grapefruit-seed extract as an antibacterial agent: II. Mechanism of action and in vitro toxicity. Heggers JP, Cottingham J, Gusman J, Reagor L, McCoy L, Carino E, Cox R, Zhao JG
Honey is a very complex substance, rich in vital elements, which make it a real supplement. Made up mainly of sugars, it also contains many mineral salts and vitamins, in particular those of groups B and C, folic acid and pantothenic acid; there are substances with antibiotic action, amino acids, proteins, hormones, enzymes etc. For this reason, honey offers numerous benefits: as a decongestant and calming cough, it increases physical strength and resistance, has a cardiotropic, hepatoprotective and detoxifying action, stimulates and regulates the digestive system, and has an anti-inflammatory action. anemic.
Sources:
Medical benefit of honeybee products. José Mauricio Sforcin, Vassya Bankova, Andrzej K. Kuropatncki. 2017: 2702106
Propolis is a resinous substance produced by bees, composed of more than 300 components including resins, balms and waxes, which vary depending on the different collection sources. To these components are added aromatic acids, pollen, essential oils, flavonoids and polyphenols, mineral salts and vitamins group B, which make it a true natural medicine. Numerous studies see propolis as the protagonist, as it has anti-inflammatory, antiviral, antimicrobial, antifungal and immunomodulatory activity. Precisely on this last point it has been seen how it modulates at a genetic level the expression of some receptors implicated in the pro-inflammatory cascade and modulates the activity of the macrophages.
Sources:
Búfalo, M. C., Bordon-Graciani, A. P., Conti, B. J., de Assis Golim, M., & Sforcin, J. M. (2014). The immunomodulatory effect of propolis on receptors expression, cytokine production and fungicidal activity of human monocytes. Journal of Pharmacy and Pharmacology, 66(10), 1497–1504
Mint is a herbaceous, perennial plant, 50-60 cm tall, equipped with a fibrous, branched rhizome. It is a renowned plant used since ancient times, both in culinary and herbal contexts, especially for its menthol content, the most active part of the phytocomplex found in the essential oil. In vitro, it has demonstrated antispasmodic activity on intestinal tissues, inhibiting the spontaneous contractility of the colon by acting on intracellular calcium influx. It is particularly indicated in cases of irritable bowel syndrome. Menthol has also shown broncomucotropic activity, meaning it stimulates the production of cellular mucus at the bronchial level.
Sources:
Assessment report on Mentha piperita aetheroleum. EMA/HMPC/349465/2006