

RS4/MIRABILUS® PETTORALIS
Fluidity of bronchial secretions – Dry cough
RS4/MIRABILUS® PETTORALIS is a syrup with a fluidifying component for seasonal disorders, it helps to counteract the major associated problems, such as dry cough, sore throat and cooling symptoms.
Sugar free, therefore suitable for use by diabetics or those intolerant to sugar.


Glass bottle 200 ml.

10 ml 4 times a day. For children aged 3 to 9 years the dosage should be halved.

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Additional Information
NO PRESERVATIVES / NO GLUTEN / NATURALLY LACTOSE FREE / FOR VEGETARIANS / WITH SWEETENERS
Any variation in flavor between the various production batches of the same product is due to the use of natural raw materials which can offer the palate different aromas based on the climatic trend seasonal.
Device of interest:
Device Respiratory
Packaging:
Glass bottle 200 ml
Mode of use:
10 ml 4 times a day. For children aged 3 to 9 years the dosage should be halved.
Shake the bottle well before of use.
Storage method:
Close the container after use, keep away from light.
Warnings: Do not exceed the recommended daily dose. Do not use in case of thyroid dysfunction. Keep out of reach of children under 3 years. Food supplements are not intended as a substitute for a varied and balanced diet and a healthy lifestyle. The possible presence of sediment is a consequence of the use of ingredients of natural origin, which does not affect the quality of the product. The information reported here is the result of our best knowledge and may be subject to change based on any changes at our sole discretion.
Ingredients
Glycyrrhiza Glabra L. root e.f.; Plantago Lanceolata L. leaves e.f.; Sweetener: Sorbitol; Althaea Officinalis L. root; Propolis e.s. 2.5% galangin; Myroxylon balsamum (L.) Harms balsam e.f./balm f.e.; Soy Lecithin; Melaleuca leucadendra var. viridiflora (Sol. ex Gaertn.) Cheel o.e.; Brassica oleracea var. italica Plenck plants with flowers e.s. tit. 10% in Sulforaphane; Sweetener: Stevia Rebaudiana.
Daily dose content
Altea
2576 mg plant in dry extract.
Propolis dry extract:
644 mg
Tolù Balsam e.f.
1288 mg
Licorice:
500 mg plant in e.f.
Plantago:
500 mg plant in e.f.
Niaouly o.e.
48 mg
Sulforaphane
0.4 mg


Bioenergetic Extraction® patent
Natural products obtained exclusively from plant extracts. A unique and innovative methodology.

High Quality
Maintains the organoleptic and health properties of the plants, thanks to ultrasonic maceration and low temperatures.

Absence of additives
We do not use excipients, sweeteners, surfactants or emulsifiers, guaranteeing a purer product.

RS4/MIRABILUS® PECTORALIS
RS4/MIRABILUS® PETTORALIS it's a syrup with a component fluidifying for seasonal disorders, helps to counteract the major associated issues, such as dry cough, sore throat and cold symptoms. The phytocomplex based on Altea, rich in plant mucilage, to which are paired Propolis, Tolu Balm, Licorice, Plantain and Sulforaphane, it is a valid aid against classic winter ailments. Sugar-free, therefore suitable for use by diabetic or sugar-intolerant individuals. Its intake is recommended in conjunction with other products from the MIRABILUS line.
Properties of natural elements
Altea
Althea is a plant of the Malvaceae family. The root extracts contain starch, pectins, mucilages, sugars, fats and tannins. In particular, the mucilages give the plant its properties emollient, soothing and protective for the mucosal membranes. For this reason it is indicated in the treatment of all forms of inflammation, such as sore throats, abscesses, stomatitis and gingivitis rhamnogalacturonan acts on serotoninergic 5HT2 receptors, inhibiting them.
Sources:
Assessment report on Althaea officinalis radix. EMA/MPC/436680/2015
Italian Propolis
Propolis is a resinous substance produced by bees, composed of more than 300 components including resins, balms and waxes, which vary depending on the different collection sources. To these components are added aromatic acids, pollen, essential oils, flavonoids and polyphenols, mineral salts and vitamins group B, which make it a true natural medicine. Numerous studies see propolis as the protagonist, as it has anti-inflammatory, antiviral, antimicrobial, antifungal and immunomodulatory activity. Precisely on this last point it has been seen how it modulates at a genetic level the expression of some receptors implicated in the pro-inflammatory cascade and modulates the activity of the macrophages.
Sources:
Búfalo, M. C., Bordon-Graciani, A. P., Conti, B. J., de Assis Golim, M., & Sforcin, J. M. (2014). The immunomodulatory effect of propolis on receptors expression, cytokine production and fungicidal activity of human monocytes. Journal of Pharmacy and Pharmacology, 66(10), 1497–1504
Sulforaphane
Sulforaphane is a compound found naturally in plants belonging to the Cruciferous family (e.g. broccoli). It is a molecule with a high antioxidant activity, such as to protect each cell from any oxidative and inflammatory damage. Sulforaphane activates many enzymes involved in cellular redox reactions and acts at a genetic level, regulating endogenous detoxifying mechanisms. For this reason it has been studied in many clinical cases, for example in the field of pulmonary pathologies, sulforaphane has been shown to increase the bronchoprotective activity of other natural agents.
In digestive pathologies, such as infections induced by Helycobacter Pilori and non-steroidal anti-inflammatories, in which there is great oxidative stress at the level of the gastrointestinal mucosa, sulforaphane has demonstrated both in vitro and in vivo to have a good antibacterial activity, therefore effective against Helycobacter pylori, and a cytoprotective role in gastritis induced by drugs.
Sources:
Role of Sulforaphane in Protection of Gastrointestinal Tract Against H. pylori and NSAID-Induced Oxidative Stress Akinori Yanaka. Division of Gastroenterology, Hitachi Medical Education and Research Center, Faculty of Medicine, University of Tsukuba, 2-1-1, Jonan-cho, Hitachi-shi, Ibaraki-ken, 317-0077, Japan
Curr Pharm Des. 2017 Aug; 23(27): 4066–4075
Fahey, J. W., & Talalay, P. (1999). Antioxidant functions of sulforaphane: a potent inducer of Phase II detoxication enzymes. Food Chem Toxicol, 37(9-10), 973-979
Sulforaphane improves the bronchoprotective response in asthmatics through Nrf2-mediated gene pathways Robert H. Brown, Curt Reynolds, Allison Brooker, Paul Talalay, and Jed W. Fahey. Respir Res. 2015; 16(1): 106
Plantain
Plantain is a plant of the Plantaginaceae family.
The dry extract obtained from the leaves contains glucosides, flavonoids (luteolin), mucilages, tannins, pectins, salic acid, salts The presence of these active ingredients gives the plant expectorant, antibacterial and anti-inflammatory properties. The latter is due to aucubin, which through hydrolysis releases aucubigenin, an active ingredient with anti-allergic and decongestant properties, whose mechanism of action is expressed in the inhibition of the synthesis of inflammatory mediators a bacteriostatic remedy against this microorganism. For this reason, plantain is used effectively in inflammatory states of the respiratory tract in general, in cases of cough, phlegm. bronchial, chronic bronchitis.
Sources:
Assessment report on Plantago lanceolata folium. EMA/HMPC/437859/2010
Licorice
Licorice is a perennial herbaceous plant belonging to the Fabaceae family. Often used in the form of sweets or liqueurs, it boasts numerous health properties given by the numerous active ingredients it contains: glycyrrhizin and carbenoxolone, mostly contained in the root, have a detected anti-ulcer activity, both for the stomach and the duodenum. They reduce the secretion of gastric juices, inhibiting the release of gastrin, a hormone present in the gastric mucosa, which regulates the release of acid. hydrochloric.
Sources:
Assessment report on Glycyrrhiza glabra L. and/or Glycyrrhiza inflata Bat. Radix EMA/HMPC/571122/2010
Althea is a plant of the Malvaceae family. The root extracts contain starch, pectins, mucilages, sugars, fats and tannins. In particular, the mucilages give the plant its properties emollient, soothing and protective for the mucosal membranes. For this reason it is indicated in the treatment of all forms of inflammation, such as sore throats, abscesses, stomatitis and gingivitis rhamnogalacturonan acts on serotoninergic 5HT2 receptors, inhibiting them.
Sources:
Assessment report on Althaea officinalis radix. EMA/MPC/436680/2015
Propolis is a resinous substance produced by bees, composed of more than 300 components including resins, balms and waxes, which vary depending on the different collection sources. To these components are added aromatic acids, pollen, essential oils, flavonoids and polyphenols, mineral salts and vitamins group B, which make it a true natural medicine. Numerous studies see propolis as the protagonist, as it has anti-inflammatory, antiviral, antimicrobial, antifungal and immunomodulatory activity. Precisely on this last point it has been seen how it modulates at a genetic level the expression of some receptors implicated in the pro-inflammatory cascade and modulates the activity of the macrophages.
Sources:
Búfalo, M. C., Bordon-Graciani, A. P., Conti, B. J., de Assis Golim, M., & Sforcin, J. M. (2014). The immunomodulatory effect of propolis on receptors expression, cytokine production and fungicidal activity of human monocytes. Journal of Pharmacy and Pharmacology, 66(10), 1497–1504
Sulforaphane is a compound found naturally in plants belonging to the Cruciferous family (e.g. broccoli). It is a molecule with a high antioxidant activity, such as to protect each cell from any oxidative and inflammatory damage. Sulforaphane activates many enzymes involved in cellular redox reactions and acts at a genetic level, regulating endogenous detoxifying mechanisms. For this reason it has been studied in many clinical cases, for example in the field of pulmonary pathologies, sulforaphane has been shown to increase the bronchoprotective activity of other natural agents.
In digestive pathologies, such as infections induced by Helycobacter Pilori and non-steroidal anti-inflammatories, in which there is great oxidative stress at the level of the gastrointestinal mucosa, sulforaphane has demonstrated both in vitro and in vivo to have a good antibacterial activity, therefore effective against Helycobacter pylori, and a cytoprotective role in gastritis induced by drugs.
Sources:
Role of Sulforaphane in Protection of Gastrointestinal Tract Against H. pylori and NSAID-Induced Oxidative Stress Akinori Yanaka. Division of Gastroenterology, Hitachi Medical Education and Research Center, Faculty of Medicine, University of Tsukuba, 2-1-1, Jonan-cho, Hitachi-shi, Ibaraki-ken, 317-0077, Japan
Curr Pharm Des. 2017 Aug; 23(27): 4066–4075
Fahey, J. W., & Talalay, P. (1999). Antioxidant functions of sulforaphane: a potent inducer of Phase II detoxication enzymes. Food Chem Toxicol, 37(9-10), 973-979
Sulforaphane improves the bronchoprotective response in asthmatics through Nrf2-mediated gene pathways Robert H. Brown, Curt Reynolds, Allison Brooker, Paul Talalay, and Jed W. Fahey. Respir Res. 2015; 16(1): 106
Plantain is a plant of the Plantaginaceae family.
The dry extract obtained from the leaves contains glucosides, flavonoids (luteolin), mucilages, tannins, pectins, salic acid, salts The presence of these active ingredients gives the plant expectorant, antibacterial and anti-inflammatory properties. The latter is due to aucubin, which through hydrolysis releases aucubigenin, an active ingredient with anti-allergic and decongestant properties, whose mechanism of action is expressed in the inhibition of the synthesis of inflammatory mediators a bacteriostatic remedy against this microorganism. For this reason, plantain is used effectively in inflammatory states of the respiratory tract in general, in cases of cough, phlegm. bronchial, chronic bronchitis.
Sources:
Assessment report on Plantago lanceolata folium. EMA/HMPC/437859/2010
Licorice is a perennial herbaceous plant belonging to the Fabaceae family. Often used in the form of sweets or liqueurs, it boasts numerous health properties given by the numerous active ingredients it contains: glycyrrhizin and carbenoxolone, mostly contained in the root, have a detected anti-ulcer activity, both for the stomach and the duodenum. They reduce the secretion of gastric juices, inhibiting the release of gastrin, a hormone present in the gastric mucosa, which regulates the release of acid. hydrochloric.
Sources:
Assessment report on Glycyrrhiza glabra L. and/or Glycyrrhiza inflata Bat. Radix EMA/HMPC/571122/2010